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TWIST2 Antibody

Catalog # Availability Size / Price Inquiry
AMM08792G 100 μl / $545

TWIST2 Antibody

Brand

Leading Biology

Catalog Number

AMM08792G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TWIST2 antibody.

Molecular Weight

18.1kDa

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11062344}. Cytoplasm. Note=Mainly nuclear during embryonic development. Cytoplasmic in adult tissues

Host

Mouse

Species Reactivity

Human

Clone

1A11D9

Isotype

IgG1

Symbol

BHLHA39, DERMO1

GeneID

UniProt ID

Function

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, FC, ICC, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000

Synonyms

Twist-related protein 2, Class A basic helix-loop-helix protein 39, bHLHa39, Dermis-expressed protein 1, Dermo-1, TWIST2, BHLHA39, DERMO1

Images

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Figure 2:Western blot analysis using TWIST2 mAb against human TWIST2 (AA: 1-160) recombinant protein. (Expected MW is 44.1 kDa)

Figure 3:Western blot analysis using TWIST2 mAb against HEK293 (1) and TWIST2 (AA: 1-160)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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