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Neuropilin-1 Antibody

Catalog # Availability Size / Price Inquiry
AMM06646G 100 μl / $545

Neuropilin-1 Antibody

Brand

Leading Biology

Catalog Number

AMM06646G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neuropilin-1 antibody.

Molecular Weight

103.1kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Clone

5B1E11

Isotype

IgG1

Symbol

NRP, VEGF165R

GeneID

UniProt ID

Function

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, FC, ICC, E

Dilution

E~~1/10000 FC~~1/200 - 1/400 WB~~1/500 - 1/2000

Synonyms

Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 2:Flow cytometric analysis of Hela cells using Neuropilin-1 mouse mAb (green) and negative control (red).

Figure 3:Western blot analysis using Neuropilin-1 mouse mAb against Jurkat (1), Hela (2), and HUVEC (3) cell lysate.

Specification

Quantity

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