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ROR2 Antibody

Catalog # Availability Size / Price Inquiry
AMR09762G 100 μl / $545

ROR2 Antibody

Brand

Leading Biology

Catalog Number

AMR09762G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ROR2 antibody.

Molecular Weight

104.8kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Clone

6F2D10

Isotype

IgG1

Symbol

NTRKR2

GeneID

UniProt ID

Function

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.

Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. ; ;

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

Synonyms

Tyrosine-protein kinase transmembrane receptor ROR2, 2.7.10.1, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using ROR2 mAb against human ROR2 (AA: 59-155) recombinant protein. (Expected MW is 36.8 kDa)

Figure 2: Western blot analysis using ROR2 mAb against HEK293 (1) and ROR2 (AA: 59-155)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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