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SERPINA7 Antibody

Catalog # Availability Size / Price Inquiry
AMM07760G 100 μl / $545

SERPINA7 Antibody

Brand

Leading Biology

Catalog Number

AMM07760G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SERPINA7 antibody.

Molecular Weight

46.3kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human

Clone

1C3H11

Isotype

IgG1

Symbol

TBG

GeneID

UniProt ID

Function

Major thyroid hormone transport protein in serum.

Summary

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. ;

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000

Synonyms

Thyroxine-binding globulin, Serpin A7, T4-binding globulin, SERPINA7, TBG

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using SERPINA7 mAb against human SERPINA7 recombinant protein. (Expected MW is 41.4 kDa)

Figure 2: Western blot analysis using SERPINA7 mAb against HEK293 (1) and SERPINA7 (AA: 168-302)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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