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DCN Antibody

Catalog # Availability Size / Price Inquiry
APR15703G 100 μl / $545

DCN Antibody

Brand

Leading Biology

Catalog Number

APR15703G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DCN antibody.

Molecular Weight

39.7kDa

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Mouse

Species Reactivity

Human

Clone

5E8E7

Isotype

IgG1

Symbol

SLRR1B

GeneID

UniProt ID

Function

May affect the rate of fibrils formation.

Summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. ;

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

Synonyms

Decorin, Bone proteoglycan II, PG-S2, PG40, DCN, SLRR1B

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using DCN mAb against human DCN recombinant protein. (Expected MW is 32.5 kDa)

Figure 2: Western blot analysis using DCN mAb against HEK293 (1) and DCN (AA: 263-324)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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