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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Fibulin-3 / EFEMP1 Antibody (clone 1D9)

Fibulin-3 / EFEMP1 Antibody (clone 1D9)

Catalog # Availability Size / Price Inquiry
APR11914G 50 μl / $495

Fibulin-3 / EFEMP1 Antibody (clone 1D9)

Brand

Leading Biology

Catalog Number

APR11914G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Fibulin-3 / EFEMP1 antibody (clone 1D9).

Molecular Weight

54641 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space. Secreted, extracellular space, extracellular matrix Note=Localizes to the lamina propria underneath the olfactory epithelium.

Host

Mouse

Species Reactivity

Human

Target

Human Fibulin-3 / EFEMP1

Clone

1D9

Isotype

IgG2a

Symbol

FBLN3, FBNL

GeneID

UniProt ID

Function

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Summary

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, Flo

Dilution

Flo (1:100), IHC-P (10 μg/ml), WB (1:200 - 1:500),

Synonyms

EFEMP1, DHRD, Extracellular protein S1-5, FBNL, FBLN3, Fibrillin-like protein, Fibrillin-like, MLVT, S1-5, MTLV, DRAD, FIBL-3, Fibulin-3

Images

Anti-Fibulin-3 / EFEMP1 antibody IHC staining of human testis.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EFEMP1...

Flow cytometry of Jurkat cells, using anti-EFEMP1 antibody (Red), compared to a nonspecific...

Specification

Quantity

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