> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > KRT18 / CK18 / Cytokeratin 18 Antibody (clone C-04, Biotin)Brand |
Leading Biology | Catalog Number |
APR17086G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KRT18 / CK18 / Cytokeratin 18 antibody (clone C-04, Biotin).
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Molecular Weight |
48058 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Nucleus, nucleolus
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Reacts with Cytokeratin 18 (45 kD). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
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Clone |
C-04
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Isotype |
IgG1
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Symbol |
CYK18
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GeneID |
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UniProt ID |
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Function |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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Summary |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, Flo
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Dilution |
Flo (1:500), IHC-P (10 μg/ml),
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Synonyms |
KRT18, CK-18, Cytokeratin 18, Cytokeratin-18, K18, Keratin 18, CYK18, Keratin-18
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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