> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > LGALS3 / Galectin 3 Antibody (clone M3/38)Brand |
Leading Biology | Catalog Number |
AMM06261G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LGALS3 / Galectin 3 antibody (clone M3/38).
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Molecular Weight |
26152 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
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Host |
Rat
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Species Reactivity |
Human, Mouse
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Clone |
M3/38
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Isotype |
IgG2a,k
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Symbol |
MAC2
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GeneID |
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UniProt ID |
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Function |
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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Summary |
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E, IHC-Fr, Flo
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Dilution |
IHC-P (10 μg/ml),
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Synonyms |
LGALS3, 35 kd lectin, 35 kDa lectin, CBP35, GAL3, Galactoside-binding protein, GALIG, IgE-binding protein, Laminin-binding protein, Gal-3, GALBP, MAC-2, Mac-2 antigen, L31, MAC2, CBP 35, Galactose-specific lectin 3, Galectin-3, L-31, Lectin L-29
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Images |
Anti-LGALS3 / Galectin 3 antibody IHC staining of human colon.
Staining of mouse PECs with 0.25 ug of rat IgG2a (open) or 0.25 ug anti-galectin-3 (closed)... |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
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