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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FOLH1 / PSMA Antibody (clone 5C4)

FOLH1 / PSMA Antibody (clone 5C4)

Catalog # Availability Size / Price Inquiry
AMM04579G 50 μl / $495

FOLH1 / PSMA Antibody (clone 5C4)

Brand

Leading Biology

Catalog Number

AMM04579G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOLH1 / PSMA antibody (clone 5C4).

Molecular Weight

84kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein

Host

Mouse

Species Reactivity

Human

Target

Human PSMA

Clone

5C4

Symbol

FOLH, NAALAD1, PSM, PSMA

GeneID

UniProt ID

Function

Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.

Summary

Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, Flo

Dilution

Flo (1:100), IHC-P (10 μg/ml), WB (1:2000)

Synonyms

Glutamate carboxypeptidase 2, 3.4.17.21, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamate carboxypeptidase II, GCPII, Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, PSM, PSMA, Pteroylpoly-gamma-glutamate carboxypeptidase, FOLH1, FOLH, NAALAD1, PSM, PSMA

Images

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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