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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Basigin / Emmprin / CD147 Antibody (clone 10E10)

Basigin / Emmprin / CD147 Antibody (clone 10E10)

Catalog # Availability Size / Price Inquiry
APG02194G 50 μl / $495

Basigin / Emmprin / CD147 Antibody (clone 10E10)

Brand

Leading Biology

Catalog Number

APG02194G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Basigin / Emmprin / CD147 antibody (clone 10E10).

Molecular Weight

42kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}

Host

Mouse

Species Reactivity

Human, Rat, Monkey, Dog

Target

Human Emmprin / CD147

Clone

10E10

GeneID

UniProt ID

Function

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Summary

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, Flo

Dilution

Flo (1:100), IF (1:100), IHC-P (10 μg/ml), WB (1:500-1:2000) ,

Synonyms

Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG

Images

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BSG...

Specification

Quantity

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