> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FAC1 / BPTF Antibody (clone 2F10)Brand |
Leading Biology | Catalog Number |
APR11891G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FAC1 / BPTF antibody (clone 2F10).
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Molecular Weight |
338kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Human FAC1 / BPTF
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Clone |
2F10
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Symbol |
FAC1, FALZ
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GeneID |
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UniProt ID |
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Function |
Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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Summary |
Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
ELISA (1:10000), IHC-P (1:50), WB (1:500-1:2000)
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Synonyms |
Nucleosome-remodeling factor subunit BPTF, Bromodomain and PHD finger-containing transcription factor, Fetal Alz-50 clone 1 protein, Fetal Alzheimer antigen, BPTF, FAC1, FALZ
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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