> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > ALK3 / BMPR1A Antibody (aa179-378, clone 4B7B2)Brand |
Leading Biology | Catalog Number |
APG01819G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ALK3 / BMPR1A antibody (aa179-378, clone 4B7B2).
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Molecular Weight |
60kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Target |
Human ALK3 / BMPR1A
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Clone |
4B7B2
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Symbol |
ACVRLK3, ALK3
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GeneID |
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UniProt ID |
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Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
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Summary |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, ICC, E, Flo
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Dilution |
ELISA (1:10000), Flo (1:200-1:400), ICC (1:200-1:1000), IHC-P (1:50), WB (1:500-1:2000)
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Synonyms |
Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, 2.7.11.30, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3
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Images |
Anti-ALK3 / BMPR1A antibody IHC staining of human skeletal muscle.
Western blot using BMPR1A monoclonal antibody against HEK293 (1) and BMPR1A (AA: 179-378)-hIgGFc...
Western blot using BMPR1A mouse monoclonal antibody against PC-3 (1), K562 (2) cell lysate, and... |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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