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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > LGALS3 / Galectin 3 Antibody (clone 1G8)

LGALS3 / Galectin 3 Antibody (clone 1G8)

Catalog # Availability Size / Price Inquiry
AMM06260G 50 μl / $495

LGALS3 / Galectin 3 Antibody (clone 1G8)

Brand

Leading Biology

Catalog Number

AMM06260G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LGALS3 / Galectin 3 antibody (clone 1G8).

Molecular Weight

26kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface

Host

Mouse

Species Reactivity

Human

Target

Human MAC-2 / Galectin-3

Clone

1G8

Symbol

MAC2

GeneID

UniProt ID

Function

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Summary

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IF (1:100), IHC-P (10 μg/ml), WB (1:200-1:4000)

Synonyms

Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2

Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LGALS3...

Western blot of extracts (35 ug) from 9 different cell lines by using anti-LGALS3 monoclonal...

Immunofluorescent staining of HeLa cells using anti-LGALS3 mouse monoclonal antibody.

Specification

Quantity

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