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HSF1 Antibody (clone 10H8)

Catalog # Availability Size / Price Inquiry
APR07828G 50 μg / $495

HSF1 Antibody (clone 10H8)

Brand

Leading Biology

Catalog Number

APR07828G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSF1 antibody (clone 10H8).

Molecular Weight

57kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules

Host

Rat

Species Reactivity

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Bovine, Guinea Pig

Target

Detects an ~85kDa protein inunstressed cell lysates, and an~95kDa protein in heat shockedcell lysates, corresponding tothe molecular mass of inactiveand active forms of HSF1 onSDS-PAGE immunoblots.

Clone

10H8

Symbol

HSTF1

GeneID

UniProt ID

Function

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Summary

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC, E, IP, GS

Dilution

IHC-P (10 μg/ml)

Synonyms

Heat shock factor protein 1, HSF 1, Heat shock transcription factor 1, HSTF 1, HSF1, HSTF1

Images

HSF1 granules present in heat-shocked mitotic cells (green) detected by IF in mitotic heat...

Anti-HSF1 antibody IHC of human kidney.

Anti-HSF1 antibody IHC of human prostate.

Specification

Quantity

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