> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > VLDLR Antibody (clone 1H10)Brand |
Leading Biology | Catalog Number |
APR10743G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VLDLR antibody (clone 1H10).
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Molecular Weight |
96kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Binds to an epitope on the C-terminus of the ligand binding domain (aa191-355) of VLDL receptor and blocks apoE4 binding.
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Clone |
1H10
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GeneID |
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UniProt ID |
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Function |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
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Summary |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
IHC-P (1:50)
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Synonyms |
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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