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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TLR2 Antibody (Extracellular Domain, clone 1030A5.138)

TLR2 Antibody (Extracellular Domain, clone 1030A5.138)

Catalog # Availability Size / Price Inquiry
APR11211G 100 μl / $495

TLR2 Antibody (Extracellular Domain, clone 1030A5.138)

Brand

Leading Biology

Catalog Number

APR11211G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR2 antibody (Extracellular Domain, clone 1030A5.138).

Molecular Weight

90kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Target

Extracellular domain of human TLR2.

Clone

1030A5.138

Symbol

TIL4

GeneID

UniProt ID

Function

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Summary

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, Flo

Dilution

IHC-P (20 μg/ml), WB (1:500),

Synonyms

Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4

Images

Western blot of TLR2 in 30 ugs of Ramos whole cell lysate using antibody at 1:500.

Anti-TLR2 antibody IHC of human tonsil.

Specification

Quantity

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