> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > MCL1 / MCL 1 Antibody (clone 8C6, 8C6D4B1)Brand |
Leading Biology | Catalog Number |
APR08385G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MCL1 / MCL 1 antibody (clone 8C6, 8C6D4B1).
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Molecular Weight |
37kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Ni-NTA purified recombinant protein MCL-1expressed in E. Coli strain M15
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Clone |
8C6, 8C6D4B1
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Symbol |
BCL2L3
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GeneID |
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UniProt ID |
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Function |
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
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Summary |
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E, IHC-Fr
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Dilution |
ELISA (1:10000), IHC-Fr (1:200-1:1000), IHC-P (1:200-1:1000), WB (1:200-1:1000) ,
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Synonyms |
Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3
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Images |
Confocal immunofluorescence of HepG2 cells using MCL1 mouse monoclonal antibody (green). |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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