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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Cytokeratin, pan (Epithelial Marker) Antibody - Purified Ab conjugated to PE

Cytokeratin, pan (Epithelial Marker) Antibody - Purified Ab conjugated to PE

Catalog # Availability Size / Price Inquiry
APR14638G 0.1 ml / $495

Cytokeratin, pan (Epithelial Marker) Antibody - Purified Ab conjugated to PE

Brand

Leading Biology

Catalog Number

APR14638G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytokeratin, pan (Epithelial Marker) antibody - Purified Ab conjugated to PE .

Molecular Weight

67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19)

Host

Mouse

Species Reactivity

Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog

Clone

SPM115 + SPM116

Isotype

Mouse / IgG's

Symbol

KRT1B

GeneID

UniProt ID

Summary

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Form

Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, FC

Synonyms

Keratin, type II cytoskeletal 1b, Cytokeratin-1B, CK-1B, Keratin-77, K77, Type-II keratin Kb39, KRT77, KRT1B

Images

Flow Cytometry of human Pan-Cytokeratins on HeLa Cells. Black: Cells alone; Green: Isotype Control; Red: PE-labeled Pan-Cytokeratin Monoclonal Antibody (SPM115 + SPM116).

Specification

Quantity

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