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ITA6 Antibody

Catalog # Availability Size / Price Inquiry
APR17796G 100 μl / $495

ITA6 Antibody

Brand

Leading Biology

Catalog Number

APR17796G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITA6 antibody.

Molecular Weight

H=119,124,107,122 KDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Cell membrane; Lipid-anchor

Host

Mouse

Species Reactivity

Human

Immunogen

324-640 aa

Target

ITA6 recombinant protein is used to produce this monoclonal antibody.

GeneID

UniProt ID

Function

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.

Summary

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

FC, IF, IHC-P, WB

Dilution

WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50 FC~~1:10~50

Synonyms

Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6, Alpha6p, ITGA6

Images

All lanes : Anti-ITA6 Antibody at 1:1000 dilution Lane 1: SW480 whole cell lysates Lane 2: human placenta lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 119 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

ITA6 Monoclonal Antibody (Cat. APR17796G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ITA6 Monoclonal Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of ITA6 Antibody ( APR17796G) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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