> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > BCL-2 AntibodyBrand |
Leading Biology | Catalog Number |
APR15117G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BCL-2 antibody.
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Molecular Weight |
26kDa
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Clone |
8E12
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC, FC, ICC, E
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Dilution |
FC~~1/200 - 1/400
IF~~1/200 - 1/1000
IHC~~1/500 - 1/2000
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Synonyms |
Apoptosis regulator Bcl-2, BCL2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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