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PAX6 Antibody

Catalog # Availability Size / Price Inquiry
APR08947G 100 μl / $495

PAX6 Antibody

Brand

Leading Biology

Catalog Number

APR08947G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAX6 antibody.

Molecular Weight

46kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

1C8

Isotype

IgG1

Symbol

AN2

GeneID

UniProt ID

Function

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1/500 - 1/2000 FC~~1/200 - 1/400

Synonyms

Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2

Images

Figure 1: Western blot analysis using PAX6 mAb against human PAX6 (AA: 1-223) recombinant protein. (Expected MW is 50 kDa)

Figure 3: Flow cytometric analysis of 3T3-L1 cells using PAX6 mouse mAb (green) and negative control (purple).

Specification

Quantity

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