> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > WASL Antibody (monoclonal) (M04)Brand |
Leading Biology | Catalog Number |
AMM08504G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality WASL antibody (monoclonal) (M04).
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Molecular Weight |
54827 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
WASL (NP_003932, 97 a.a. ~ 184 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
5F4
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Isotype |
IgG2b Kappa
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GeneID |
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UniProt ID |
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Summary |
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, IF
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Dilution |
WB~~1:500~1000
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Synonyms |
Neural Wiskott-Aldrich syndrome protein, N-WASP, WASL
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.42 KDa) .
WASL monoclonal antibody (M04), clone 5F4 Western Blot analysis of WASL expression in IMR-32 ( (Cat AMM08504G )
Immunoperoxidase of monoclonal antibody to WASL on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.8 ug/ml] |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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