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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > VNN1 Antibody (monoclonal) (M05)

VNN1 Antibody (monoclonal) (M05)

Catalog # Availability Size / Price Inquiry
APR10747G 100 μg / $495

VNN1 Antibody (monoclonal) (M05)

Brand

Leading Biology

Catalog Number

APR10747G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VNN1 antibody (monoclonal) (M05).

Molecular Weight

57012 Da

Host

mouse

Species Reactivity

Human

Target

VNN1 (NP_004657, 298 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2B10

Isotype

IgG2a Kappa

GeneID

UniProt ID

Summary

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IP, E

Synonyms

Pantetheinase, Pantetheine hydrolase, Tiff66, Vascular non-inflammatory molecule 1, Vanin-1, VNN1

Images

Immunoprecipitation of VNN1 transfected lysate using anti-VNN1 monoclonal antibody and Protein A Magnetic Bead (<a href="products_detail.asp?Catalog_id=U0007">U0007</a>), and immunoblotted with VNN1 MaxPab rabbit polyclonal antibody.

Detection limit for recombinant GST tagged VNN1 is approximately 0.1ng/ml as a capture antibody.

Specification

Quantity

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