• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > UMPS Antibody (monoclonal) (M05)

UMPS Antibody (monoclonal) (M05)

Catalog # Availability Size / Price Inquiry
APR10659G 100 μg / $495

UMPS Antibody (monoclonal) (M05)

Brand

Leading Biology

Catalog Number

APR10659G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UMPS antibody (monoclonal) (M05).

Molecular Weight

52222 Da

Host

mouse

Species Reactivity

Human

Target

UMPS (NP_000364, 381 a.a. ~ 479 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2F5

Isotype

IgG2b Kappa

GeneID

UniProt ID

Summary

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

WB~~1:500~1000

Synonyms

Uridine 5'-monophosphate synthase, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, Orotidine 5'-phosphate decarboxylase, ODC, OMPdecase, UMPS

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

Western Blot analysis of UMPS expression in transfected 293T cell line by UMPS monoclonal antibody (M05), clone 2F5. Lane 1: UMPS transfected lysate(52.2 KDa). Lane 2: Non-transfected lysate.

Immunofluorescence of monoclonal antibody to UMPS on HeLa cell . [antibody concentration 10 ug/ml]

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology APG02467G CCK4 / PTK7 Antibody (clone 4F9) 50 μl Monoclonal Antibodies
$495.00 Add Ask
2 Leading Biology AMM04683G GALT Antibody (clone 4C11) 50 μg Monoclonal Antibodies
$545.00 Add Ask
3 Leading Biology AMM01402G Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
4 Leading Biology APR08280G LTA4H / LTA4 Antibody (clone 9G8) 50 μl Monoclonal Antibodies
$495.00 Add Ask
5 Leading Biology AMM00172G CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
6 Leading Biology AMM05750G CEBPA Antibody 100 μl Monoclonal Antibodies
$545.00 Add Ask

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list