> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TPO Antibody (monoclonal) (M08)Brand |
Leading Biology | Catalog Number |
APR10526G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TPO antibody (monoclonal) (M08).
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Molecular Weight |
102963 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
TPO (NP_000538.3, 672 a.a. ~ 779 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
2A11
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Isotype |
IgG2b Kappa
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GeneID |
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UniProt ID |
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Summary |
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:500~1000
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Synonyms |
Thyroid peroxidase, TPO, TPO
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) .
Western Blot analysis of TPO expression in transfected 293T cell line by TPO monoclonal antibody (M08), clone 2A11. Lane 1: TPO transfected lysate(102.9 KDa). Lane 2: Non-transfected lysate.
Detection limit for recombinant GST tagged TPO is approximately 1ng/ml as a capture antibody. |
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Specification |
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Quantity |
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2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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