> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > SQSTM1 Antibody (monoclonal) (M01)Brand |
Leading Biology | Catalog Number |
APR07188G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SQSTM1 antibody (monoclonal) (M01).
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Molecular Weight |
47687 Da
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Target |
SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
2C11
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Isotype |
IgG2a kappa
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GeneID |
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UniProt ID |
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Summary |
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, E
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Dilution |
WB~~1:500~1000
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Synonyms |
Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, p60, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, SQSTM1, ORCA, OSIL
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (74.14 KDa) .
Immunofluorescence of monoclonal antibody to SQSTM1 on HeLa cell. [antibody concentration 10 ug/ml]
Detection limit for recombinant GST tagged SQSTM1 is approximately 0.03ng/ml as a capture antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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