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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > SHMT1 Antibody (monoclonal) (M01)

SHMT1 Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
APR09930G 100 μg / $495

SHMT1 Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

APR09930G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SHMT1 antibody (monoclonal) (M01).

Molecular Weight

53083 Da

Host

mouse

Species Reactivity

Human

Target

SHMT1 (NP_004160, 374 a.a. ~ 482 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

4F9

Isotype

IgG1 Kappa

GeneID

UniProt ID

Summary

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Dilution

WB~~1:500~1000

Synonyms

Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase, SHMT1

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .

SHMT1 monoclonal antibody (M01), clone 4F9 Western Blot analysis of SHMT1 expression in HeLa ( (Cat APR09930G )

Western Blot analysis of SHMT1 expression in transfected 293T cell line by SHMT1 monoclonal antibody (M01), clone 4F9. Lane 1: SHMT1 transfected lysate(53.1 KDa). Lane 2: Non-transfected lysate.

Specification

Quantity

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