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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > IL1B Antibody (monoclonal) (M01)

IL1B Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
APR07984G 100 μg / $495

IL1B Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

APR07984G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL1B antibody (monoclonal) (M01).

Molecular Weight

30748 Da

Host

mouse

Species Reactivity

Human

Target

IL1B (AAH08678, 170 a.a. ~ 269 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2A8

Isotype

IgG2b Kappa

GeneID

UniProt ID

Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, IP, E

Dilution

WB~~1:500~1000

Synonyms

Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

IL1B monoclonal antibody (M01), clone 2A8. Western Blot analysis of IL1B expression in human liver.

Immunofluorescence of monoclonal antibody to IL1B on HeLa cell . [antibody concentration 10 ug/ml]

Specification

Quantity

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