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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > COL4A6 Antibody (monoclonal) (M01)

COL4A6 Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
APR15535G 100 μg / $495

COL4A6 Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

APR15535G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COL4A6 antibody (monoclonal) (M01).

Molecular Weight

163807 Da

Host

mouse

Species Reactivity

Human

Target

COL4A6 (AAH05305, 1 a.a. ~ 73 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

1G11

Isotype

IgG2a Kappa

GeneID

UniProt ID

Summary

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Synonyms

Collagen alpha-6(IV) chain, COL4A6

Images

Detection limit for recombinant GST tagged COL4A6 is approximately 1ng/ml as a capture antibody.

Proximity Ligation Analysis of protein-protein interactions between OSM and COL4A6. HeLa cells were stained with anti-OSM rabbit purified polyclonal 1:1200 and anti-COL4A6 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Specification

Quantity

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