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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > ALDOB Antibody (monoclonal) (M01)

ALDOB Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
APG01802G 100 μg / $495

ALDOB Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

APG01802G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALDOB antibody (monoclonal) (M01).

Molecular Weight

39473 Da

Host

mouse

Species Reactivity

Human

Target

ALDOB (AAH29399, 1 a.a. ~ 316 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

3B3

Isotype

IgG2a kappa

GeneID

UniProt ID

Summary

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Synonyms

Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB

Images

Detection limit for recombinant GST tagged ALDOB is approximately 0.3ng/ml as a capture antibody.

Specification

Quantity

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