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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HLA-Aw32 & HLA-A25 (MHC I) Antibody

HLA-Aw32 & HLA-A25 (MHC I) Antibody

Catalog # Availability Size / Price Inquiry
APR10960G 7 ml / $495

HLA-Aw32 & HLA-A25 (MHC I) Antibody

Brand

Leading Biology

Catalog Number

APR10960G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HLA-Aw32 & HLA-A25 (MHC I) antibody.

Molecular Weight

kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Clone

SPM418

Isotype

Mouse / IgG2a, kappa

Symbol

HLAB

GeneID

UniProt ID

Function

Involved in the presentation of foreign antigens to the immune system.

Summary

This MAb reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This MAb is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, IF, FC

Synonyms

HLA class I histocompatibility antigen, B-7 alpha chain, MHC class I antigen B*7, HLA-B, HLAB

Images

Formalin-fixed, paraffin-embedded human Tonsil stained with MHC I Monoclonal Antibody (SPM418).

Specification

Quantity

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