> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > PARL AntibodyBrand |
Leading Biology | Catalog Number |
APR08926G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PARL antibody.
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Molecular Weight |
42190 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
8C4B2; 1H12E10
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Isotype |
IgG2b
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Symbol |
PSARL
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GeneID |
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UniProt ID |
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Function |
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1/500 - 1/2000
IHC~~1:200~~1000
IF~~1:200~1000.
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Synonyms |
Presenilins-associated rhomboid-like protein, mitochondrial, 3.4.21.105, Mitochondrial intramembrane cleaving protease PARL, P-beta, Pbeta, PARL, PSARL
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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