> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > UCHL1 / PGP9.5 AntibodyBrand |
Leading Biology | Catalog Number |
APR13908G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UCHL1 / PGP9.5 antibody.
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Molecular Weight |
25 KDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. Note=About 30% of total UCHL1 is associated with membranes in brain
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Host |
Mouse
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Species Reactivity |
Human
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GeneID |
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UniProt ID |
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Function |
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
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Summary |
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
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Form |
Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide, 50% glycerol, 0.1%BSA |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, ICC
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Dilution |
WB~~1:1000
ICC~~1:300
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Synonyms |
UCHL1 / PGP9.5;UCHL1;B220;CD 45;CD45;cd45 antigen;ec3.1.3.48;GP 180;GP180;Human homolog of severe combined immunodeficiency due to PTPRC deficiency;L CA;L-CA;lca;Leukocyte common antigen;LY 5;LY5;Protein tyrosine phosphatase receptor type C;Protein tyrosine phosphatase receptor type c polypeptide;PTPRC;PTPRC_HUMAN;Receptor-type tyrosine-protein phosphatase C;SCID due to PTPRC deficiency;t200;T200 glycoprotein;T200 leukocyte common antigen.
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Images |
Western blot detection of UCHL1 / PGP9.5 in U251,Raji and IMR32 cell lysates and using UCHL1 / PGP9.5 mouse mAb (1:1000 diluted).Predicted band size: 25KDa.Observed band size:25KDa.
Immunocytochemistry stain of COS7 using UCHL1 / PGP9.5 mouse mAb (1:300). |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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