> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > SOD2 AntibodyBrand |
Leading Biology | Catalog Number |
APR10198G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOD2 antibody.
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Molecular Weight |
24722 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion matrix.
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Purified His-tagged SOD protein(Fragment) was used to produced this monoclonal antibody.
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Clone |
37CT127.5.11.6
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Isotype |
IgG1κ
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GeneID |
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UniProt ID |
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Function |
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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Summary |
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Form |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, WB, E
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Dilution |
WB~~1:2000
IHC-P~~1:10~50
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Synonyms |
Superoxide dismutase [Mn], mitochondrial, SOD2
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Images |
All lanes : Anti-SD Antibody at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: human brain lysates Lane 3: human heart lysates Lane 4: human liver lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 Monoclonal Antibody (Cat. APR10198G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot analysis of anti-SOD2 Monoclonal Antibody (Cat. APR10198G) by SOD2-GST fusion protein (GST MW=26 kD. SOD2-GST fusion protein (arrow) was detected using the purified Mab. (1:2000) |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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