> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > RTN3 AntibodyBrand |
Leading Biology | Catalog Number |
AMR09785G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RTN3 antibody.
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Molecular Weight |
113kDa
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
10A8
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Isotype |
IgG2a
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Symbol |
ASYIP, NSPL2
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GeneID |
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UniProt ID |
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Function |
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC, E
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Dilution |
IHC~~1/200 - 1/1000
ICC~~1:200~~1000
IF~~1:200~1000.
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Synonyms |
Reticulon-3, Homolog of ASY protein, HAP, Neuroendocrine-specific protein-like 2, NSP-like protein 2, Neuroendocrine-specific protein-like II, NSP-like protein II, NSPLII, RTN3, ASYIP, NSPL2
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Images |
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and breast cancer (right) using RTN3 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded human Liver tissues using RTN3 mouse mAb
Figure 1: Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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