> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > DRD4 Antibody (Center) (Ascites)Brand |
Leading Biology | Catalog Number |
APR11793G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DRD4 antibody (Center) (Ascites).
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Molecular Weight |
48361 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Immunogen |
365-391 aa
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Target |
This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.
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Clone |
625CT1.5.4
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
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Summary |
This gene encodes the D4 subtype of the dopamine receptor.The D4 subtype is a G-protein coupled receptor which inhibitsadenylyl cyclase. It is a target for drugs which treatschizophrenia and Parkinson disease. Mutations in this gene havebeen associated with various behavioral phenotypes, includingautonomic nervous system dysfunction, attentiondeficit/hyperactivity disorder, and the personality trait ofnovelty seeking. This gene contains a polymorphic number (2-10copies) of tandem 48 nt repeats; the sequence shown contains fourrepeats.
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Form |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:500~8000
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Synonyms |
D(4) dopamine receptor, D(2C) dopamine receptor, Dopamine D4 receptor, DRD4
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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