> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FASN Antibody (Center) (Ascites)Brand |
Leading Biology | Catalog Number |
AMM04514G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FASN antibody (Center) (Ascites).
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Molecular Weight |
273427 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Immunogen |
942-973 aa
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Target |
This FASN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 942-973 amino acids from the Central region of human FASN.
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Clone |
497CT15.2.5
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Isotype |
IgM
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Symbol |
FAS
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GeneID |
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UniProt ID |
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Function |
Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
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Summary |
The enzyme encoded by this gene is a multifunctionalprotein. Its main function is to catalyze the synthesis ofpalmitate from acetyl-CoA and malonyl-CoA, in the presence ofNADPH, into long-chain saturated fatty acids. In some cancer celllines, this protein has been found to be fused with estrogenreceptor-alpha (ER-alpha), in which the N-terminus of FAS is fusedin-frame with the C-terminus of ER-alpha.
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Form |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IF, WB, E
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Dilution |
IF~~1:200
WB~~1:100~1000
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Synonyms |
Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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