> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FCGR3A Antibody (Ascites)Brand |
Leading Biology | Catalog Number |
APR15940G |
Product Type |
Monoclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FCGR3A antibody (Ascites).
|
||
Molecular Weight |
29089 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor
|
||
Host |
Mouse
|
||
Species Reactivity |
Human
|
||
Immunogen |
60-88 aa
|
||
Target |
This FCGR3A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from human FCGR3A.
|
||
Clone |
441CT4.2.1
|
||
Isotype |
IgG1
|
||
Symbol |
CD16A, FCG3, FCGR3, IGFR3
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
|
||
Summary |
This gene encodes a receptor for the Fc portion ofimmunoglobulin G, and it is involved in the removal ofantigen-antibody complexes from the circulation, as well as otherother antibody-dependent responses. This gene (FCGR3A) is highlysimilar to another nearby gene (FCGR3B) located on chromosome 1.The receptor encoded by this gene is expressed on natural killer(NK) cells as an integral membrane glycoprotein anchored through atransmembrane peptide, whereas FCGR3B is expressed onpolymorphonuclear neutrophils (PMN) where the receptor is anchoredthrough a phosphatidylinositol (PI) linkage. Mutations in this genehave been linked to susceptibility to recurrent viral infections,susceptibility to systemic lupus erythematosus, and alloimmuneneonatal neutropenia. Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
|
||
Form |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, E
|
||
Dilution |
WB~~1:100~400
|
||
Synonyms |
Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APG02467G | CCK4 / PTK7 Antibody (clone 4F9) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | AMM04683G | GALT Antibody (clone 4C11) | 50 μg | Monoclonal Antibodies |
|
$545.00 | Add Ask | ||
| 3 | Leading Biology | AMM01402G | Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 4 | Leading Biology | APR08280G | LTA4H / LTA4 Antibody (clone 9G8) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | AMM00172G | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 6 | Leading Biology | AMM05750G | CEBPA Antibody | 100 μl | Monoclonal Antibodies |
|
$545.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
