> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > ITGAX/CD11c Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR16921G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ITGAX/CD11c antibody (N-term).
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Molecular Weight |
127829 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
246-274 aa
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Target |
This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c.
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Clone |
428CT12.2.6.4
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Isotype |
IgG1
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Symbol |
CD11C
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GeneID |
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UniProt ID |
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Function |
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
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Summary |
This gene encodes the integrin alpha X chain protein.Integrins are heterodimeric integral membrane proteins composed ofan alpha chain and a beta chain. This protein combines with thebeta 2 chain (ITGB2) to form a leukocyte-specific integrin referredto as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2complex seems to overlap the properties of the alpha M beta 2integrin in the adherence of neutrophils and monocytes tostimulated endothelium cells, and in the phagocytosis of complementcoated particles.
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Form |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~500
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Synonyms |
Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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