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LAMP2 Antibody

Catalog # Availability Size / Price Inquiry
APR08129G 100 μl / $495

LAMP2 Antibody

Brand

Leading Biology

Catalog Number

APR08129G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LAMP2 antibody.

Molecular Weight

44961 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein {ECO:0000255|PROSITE- ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Endosome membrane; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Lysosome membrane {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}; Single-pass type I membrane protein {ECO:0000255|PROSITE-ProRule:PRU00740, ECO:0000269|PubMed:17897319}. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane

Host

Mouse

Species Reactivity

Mouse

Target

This LAMP2 monoclonal antibody is generated from mouse immunized with LAMP2 recombinant protein.

Clone

157CT16.6.6

Isotype

IgG1,K

GeneID

UniProt ID

Function

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Summary

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

WB~~1:100~1000 IF~~1:10~50

Synonyms

Lysosome-associated membrane glycoprotein 2, LAMP-2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, CD107b, LAMP2

Images

LAMP2 Antibody (Cat. APR08129G) western blot analysis in mouse NIH-3T3 cell line lysates (35μg/lane).This demonstrates the LAMP2 antibody detected the LAMP2 protein (arrow).

Confocal immunofluorescent analysis of LAMP2 Antibody ( APR08129G) with HepG2 cell followed by Alexa Fluor? 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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