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TBB1 Antibody

Catalog # Availability Size / Price Inquiry
AMM08112G 100 μl / $495

TBB1 Antibody

Brand

Leading Biology

Catalog Number

AMM08112G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TBB1 antibody.

Molecular Weight

50327 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton

Host

Mouse

Species Reactivity

Human, Mouse

Target

This monoclonal antibody is generated from mice immunized with a recombinant protein human TBB1.

Clone

86CT4.4.4

Isotype

Mouse IgG1

GeneID

UniProt ID

Function

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).

Summary

This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

WB~~1:100~500 IHC-P~~1:10~50 IF~~1:10~50

Synonyms

Tubulin beta-1 chain, TUBB1

Images

All lanes : Anti-TBB1 Antibody at 1:1000 dilution Lane 1: CCRF-CEM whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of anti-TBB1 Antibody (Cat. AMM08112G) in mouse brain tissue, Y79, CEM and 293 lysates (35μg/lane). TBB1 (arrow) was detected using the purified Mab.(1μg/ml)

Formalin-fixed and paraffin-embedded human brain reacted with TBB1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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