> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Antibody - With BSA and AzideBrand |
Leading Biology | Catalog Number |
APR14595G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) antibody - With BSA and Azide.
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Molecular Weight |
40-57kDa
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Host |
Mouse
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Species Reactivity |
Human, Mouse, Rat
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Target |
Solubilized keratin extract from human stratum corneum
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Clone |
AE-1
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Isotype |
IgG1
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Symbol |
KPP
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GeneID |
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UniProt ID |
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Summary |
This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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Form |
0.5 ml at 200ug/ml with BSA and azide |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC, IF, FC, IP, E
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Synonyms |
Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP
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Images |
Formalin-fixed, paraffin-embedded skin stained with Cytokeratin, LMW Ab (AE1)
Western blot analysis of A431 lysate using Cytokeratin, LMW Ab (AE-1). |
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Specification |
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Quantity |
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| 5 | Leading Biology | AMM00172G | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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