> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > GSTA1 AntibodyBrand |
Leading Biology | Catalog Number |
APR10881G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GSTA1 antibody.
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Molecular Weight |
25631 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Mouse
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Species Reactivity |
Human
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Target |
This GSTA1 monoclonal antibody is generated from mouse immunized with GSTA1 recombinant protein.
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Clone |
286CT8.1.5
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Isotype |
IgM,k
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GeneID |
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UniProt ID |
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Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
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Summary |
Cytosolic and membrane-bound forms of glutathioneS-transferase are encoded by two distinct supergene families. Theseenzymes function in the detoxification of electrophilic compounds,including carcinogens, therapeutic drugs, environmental toxins andproducts of oxidative stress, by conjugation with glutathione. Thegenes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibilityto carcinogens and toxins as well as affect the toxicity andefficacy of some drugs. At present, eight distinct classes of thesoluble cytoplasmic mammalian glutathione S-transferases have beenidentified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alphaclass. The alpha class genes, located in a cluster mapped tochromosome 6, are the most abundantly expressed glutathioneS-transferases in liver. In addition to metabolizing bilirubin andcertain anti-cancer drugs in the liver, the alpha class of theseenzymes exhibit glutathione peroxidase activity thereby protectingthe cells from reactive oxygen species and the products ofperoxidation.
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Form |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100
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Synonyms |
Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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