> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > SCARF1 AntibodyBrand |
Leading Biology | Catalog Number |
AMR09822G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SCARF1 antibody.
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Molecular Weight |
87387 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
A synthetic peptide corresponding to residues in human SCARF1 was used as an immunogen.
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Clone |
EPR3848
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Symbol |
KIAA0149, SREC
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GeneID |
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UniProt ID |
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Function |
Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity).
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Summary |
Scavenger receptor class F member 1 (SCARF1) mediates the selective uptake of modified low density lipoprotein (LDL), such as acetylated LDL and oxidized LDL, into endothelial cells (1). It also mediates heterophilic interactions, suggesting that it functions as an adhesion protein (2). SCARF1 has several characteristic domain structures; an N-terminal extracellular domain with seven epidermal growth factor (EGF)-like cysteine pattern signatures, and an unusually long C-terminal cytoplasmic domain composed of a Ser/Pro-rich region followed by a Gly-rich region. SCARF1 is expressed at high levels in endothelial cells but not in smooth muscle cells (1).
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Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~1:1000~10000
IHC~~1:250~500
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Synonyms |
Scavenger receptor class F member 1, Acetyl LDL receptor, Scavenger receptor expressed by endothelial cells 1, SREC-I, SCARF1, KIAA0149, SREC
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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