> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Prealbumin AntibodyBrand |
Leading Biology | Catalog Number |
APR12960G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Prealbumin antibody.
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Molecular Weight |
15887 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
A synthetic peptide corresponding to residues in human Prealbumin was used as an immunogen.
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Clone |
EPR3219
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Symbol |
PALB
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GeneID |
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UniProt ID |
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Function |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
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Summary |
Prealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). It is reported to be either selectively transported across or synthesized within the blood-CSF barrier (3). Over 80 different disease-causing mutations in prealbumin have been reported. The vast majority is inherited in an autosomal dominant manner and is related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. A small portion of prealbumin mutations are apparently non-amyloidogenic (4). The human amyloid disorders, familial amyloid polyneuropathy, familial amyloid cardiomyopathy and senile systemic amyloidosis, are caused by insoluble prealbumin fibrils (2).
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Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~1:1000~5000
IHC~~1:100~250
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Synonyms |
Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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