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Myoglobin Antibody

Catalog # Availability Size / Price Inquiry
APR07137G 100 μl / $545

Myoglobin Antibody

Brand

Leading Biology

Catalog Number

APR07137G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Myoglobin antibody.

Molecular Weight

17184 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

A synthetic peptide corresponding to residues on the C-terminus of human myglobin was used as an immunogen.

Clone

EP3081Y

GeneID

UniProt ID

Function

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Summary

Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration during periods of high physiological demand (1). Myoglobin may serve a variety of functions in muscular oxygen supply, such as oxygen storage, facilitated O(2) diffusion, and myoglobin-mediated oxidative phosphorylation. Disruption of myoglobin results in the activation of multiple compensatory mechanisms that steepen the pO(2) gradient and reduce the diffusion path length for O(2) between capillary and the mitochondria (2).

Form

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Dilution

WB~~1:1000~5000 IHC~~1:250~500

Synonyms

Myoglobin, MB

Images

A. Western blot analysis on (A) human muscle (B) mouse muscle and (C) rat muscle tissue lysate using anti-myglobin RabMAb (Cat. APR07137G), dilution 1:5000.

B. Immunohistochemical analysis of paraffin-embedded human heart muscles using anti-Myoglobin RabMAb (Cat. APR07137G).

Specification

Quantity

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