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INPP4A Antibody

Catalog # Availability Size / Price Inquiry
APR16859G 100 μl / $545

INPP4A Antibody

Brand

Leading Biology

Catalog Number

APR16859G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality INPP4A antibody.

Molecular Weight

109956 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

A synthetic peptide corresponding to residues near the C-terminus of human INPP4A was used as an immunogen.

Clone

EPR3426

GeneID

UniProt ID

Function

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.

Summary

Inositol polyphosphate 4-phosphatase (INPP4A), an enzyme of the inositol phosphate signaling pathway, catalyzes the hydrolysis of the 4-position phosphate of inositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and phosphatidylinositol 3,4-bisphosphate (1). Hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate has been implicated in mitogenesis mediated by PDGF receptor, the oxidative burst of neutrophils, and translocation of the glucose transporter to the plasma membrane (2).

Form

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:1000~2000

Synonyms

Type I inositol 3, 4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type I, INPP4A

Images

A. Western blot analysis on (A) fetal brain tissue lysate and (B) Jurkat cell lysate using anti-INPP4A RabMAb (Cat. APR16859G).

Specification

Quantity

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