> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HNRPUL1 AntibodyBrand |
Leading Biology | Catalog Number |
AMM05387G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HNRPUL1 antibody.
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Molecular Weight |
95739 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
A synthetic peptide corresponding to residues on the C-terminus of human HNRPUL1 was used as an immunogen.
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Clone |
EP2633Y
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Symbol |
E1BAP5, HNRPUL1
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GeneID |
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UniProt ID |
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Function |
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
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Summary |
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRPUL1) is a nuclear RNA binding protein belonging to hnRNP family.(1) HNRPUL1 interacts with adenovirus type 5 (Ad5) E1B-55 kDa, BRD7, HRMT1L1, TP53, and TAP. As a basic transcriptional regulator, HNRPUL1 represses basic transcription driven by various virus and cellular promoters. In association with BRD7, HNRPUL1 activates glucocorticoid-responsive promoter transcription in the absence of ligand-stimulation. HNRPUL1 might play an important role in nucleocytoplasmic mRNA processing and transport (2). Due to alternative splicing, five different isoform of HNRPUL1 exist.
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Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~1:1000~10000
IHC~~1:250~500
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Synonyms |
Heterogeneous nuclear ribonucleoprotein U-like protein 1, Adenovirus early region 1B-associated protein 5, E1B-55 kDa-associated protein 5, E1B-AP5, HNRNPUL1, E1BAP5, HNRPUL1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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