> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Apolipoprotein CIII AntibodyBrand |
Leading Biology | Catalog Number |
APR07064G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Apolipoprotein CIII antibody.
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Molecular Weight |
10852 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
A synthetic corresponding to C-terminus of human Apolipoprotein CIII was used as immunogen.
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Clone |
EP1372Y
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GeneID |
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UniProt ID |
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Function |
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.
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Summary |
Apolipoprotein CIII (Apo CIII) is one of 9 known polymorphic forms of apolipoproteins. The apolipoproteins function as stabilizers of intact lipoprotein particles. Specifically, Apo CIII is a very low density lipoprotein (VLDL) protein (1). Apo CIII is involved in inhibition of lipoprotein and hepatic lipases. It is thought to delay catabolism of triglyceride-rich particles. A defect in Apo CIII has been linked to hyperalphalipoproteinemia (HLAP), which causes increased levels of high density lipoprotein (HDL) (2).
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Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Dilution |
WB~~1:2000~10000
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Synonyms |
Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3, APOC3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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