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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TOP2A / Topoisomerase II Alpha Antibody (clone 1E2)

TOP2A / Topoisomerase II Alpha Antibody (clone 1E2)

Catalog # Availability Size / Price Inquiry
AMM01928G 50 μg / $545

TOP2A / Topoisomerase II Alpha Antibody (clone 1E2)

Brand

Leading Biology

Catalog Number

AMM01928G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TOP2A / Topoisomerase II Alpha Antibody (clone 1E2).

Molecular Weight

174kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm

Host

Mouse

Species Reactivity

Human

Clone

1E2

Symbol

TOP2

GeneID

UniProt ID

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

Summary

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)

Images

TOP2A monoclonal antibody clone 1E2 Western blot of TOP2A expression in HeLa NE.

Immunofluorescence of monoclonal antibody to TOP2A on HeLa cell (antibody concentration 10 ug/ml).

Anti-TOP2A antibody IHC of human spleen.

Specification

Quantity

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