> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TOP2A / Topoisomerase II Alpha Antibody (clone 1E2)Brand |
Leading Biology | Catalog Number |
AMM01928G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TOP2A / Topoisomerase II Alpha Antibody (clone 1E2).
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Molecular Weight |
174kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
1E2
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Symbol |
TOP2
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GeneID |
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UniProt ID |
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Function |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
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Summary |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)
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Images |
TOP2A monoclonal antibody clone 1E2 Western blot of TOP2A expression in HeLa NE.
Immunofluorescence of monoclonal antibody to TOP2A on HeLa cell (antibody concentration 10 ug/ml).
Anti-TOP2A antibody IHC of human spleen. |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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